Chelsea are optimistic that Cole Palmer, Joao Pedro, and Reece James will feature against Bournemouth on October 10.
Palmer withdrew from the England squad due to a minor muscle injury, as the coaching staff want to manage his fitness carefully to avoid recurrence of last year's groin issues.
Joao Pedro has been sidelined with a knee injury sustained in the 2-2 draw against Hull City. This setback also ruled him out of the Brentford match and a call-up to the Brazil squad.
Reece James is on the mend from hamstring problems. England manager Thomas Tuchel provided an update on the defender's condition.
He tried, we were waiting until this morning, but he couldn't make it. Now we have enough time to prepare for the next game. He was very close to being fit.
The return of this trio would be a massive boost for the Blues' head coach Xabi Alonso. Additionally, by October 10, Moises Caicedo, who has only played 14 minutes this season, and summer signings Marco Palastra and Emmanuel Emega may also recover in time to make their debuts.
However, during the international break, Chelsea received some troubling news. Mike Penders picked up a thigh injury in training with the Belgium squad, while Jamie Gittens injured his ankle in an England U21 match against Kazakhstan, leaving the pitch on crutches. Recovery timelines for both players remain unclear.
